Republished with permission of Momentum,

a School of Engineering electronic publication.

Dr. Leslie Shor of Chemical & Biomolecular Engineering specializes in recreating very small habitats – smaller than the width of a human hair in some cases. Building from scratch a simulated habitat that might sustain up to a thousand different organisms that each need different conditions to survive is no easy trick.

But the potential payoffs can be huge – more sustainable agriculture, better ways to fight infection, or more sustainable energy production from biofuels.

One particular project in her lab prompted DuPont to name her a 2014 Young Professor. The annual program recognizes professors engaged in innovative research that addresses global challenges regarding food, energy and production. Shor, one of 10 professors to receive the appointment, will receive $75,000 over the next three years to support their research.

The project that won DuPont’s attention is the same one that won a Grand Challenges Exploration grant of $100,000 from the Bill and Melinda Gates Foundation in 2012.

Hunger and poverty affect 1 billion people. Population growth, changing consumption habits, and a shifting climate will only magnify the problem. So developing new ways to increase food production is crucial. To that end, Shor and other researchers in her lab hope to find a new way to increase crop yields. For this research, she teamed up with Daniel J. Gage (Molecular & Cell Biology), a microbiologist with expertise in the rhizosphere. That’s the region of soil around a plant’s roots where crucial nutrients are absorbed. Beneficial bacteria in the rhizosphere can help plants by inhibiting pathogens and producing antibiotics. The rhizosphere is also home to protozoa – a kingdom of single-celled animals with the ability to move efficiently in soil. That’s where Shor comes in, with her knowledge of artificial microbial habitats and how protozoa migrate in micro-structured environments.

With her collaborators and students, Shor seeks to increase crop yields by using protozoa to distribute bacteria along growing roots. Currently, applications of biologicals or agrichemicals are not targeted, leading to inefficiency and adverse environmental impacts. Solving one problem might lead to the creation of several more. In Shor’s lab, they’re trying to use the environment as part its own solution.

“The soil system is an incredibly complex habitat, and it’s home to organisms from all five kingdoms – plants, animals protista fungi and archae – are all present in the soil,” she said. They interact with each other, and with the air, water, organic matter and soil grains in complex ways. Typically, microbiologists will take organisms out of their natural habitat and put them into an overly simplified lab habitat.

“There’s no microstructure in those habitats, typically,” she said. “Our microhabitats are not the same thing as real soil, but they do contain some of its features. Our microhabitats offer a window into the microworld.”

Dr. Cato T. Laurencin, a Professor of Chemical and Biomolecular Engineering and designated University Professor at UCONN has been named a Fellow of the American Chemical Society.

“The scientists selected as this year’s class of ACS fellows are truly a dedicated group,” said ACS President Tom Barton, Ph.D. “Their outstanding contributions to advancing chemistry through service to the Society are many. In their quest to improve people’s lives through the transforming power of chemistry, they are helping us to fulfill the vision of the American Chemical Society.”

Laurencin, an internationally recognized engineer, scientist and orthopedic surgeon, holds the titles of University Professor and Albert and Wilda Van Dusen Distinguished Professor of Orthopaedic Surgery. He also is a Professor of Materials Sciences and Engineering, and a Professor of Biomedical Engineering. He is the director of UConn Health’s Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences and founding director of UConn Health’s Institute for Regenerative Engineering. He is the Chief Executive Officer of UConn’s cross-university translational institute, the Connecticut Institute for Clinical and Translational Science.

“This is a great honor,” Laurencin said. “The American Chemical Society is one of our nation’s largest science organizations and has made great contributions to the field.”

Laurencin was cited for his seminal contributions in polymer science and polymer-ceramic systems applied to biology. Well-known for his groundbreaking work in biomaterials, he has patented and invented a number of breakthrough technologies. These include the L-C Ligament, the first bioengineered matrix that completely regenerates ligament tissue inside the knee. A Fellow of the American Institute of Chemical Engineers, Dr. Laurencin was named one of the 100 Engineers of the Modern Era at its Centennial celebration. He is an elected member of both the Institute of Medicine of the National Academy of Sciences, and the National Academy of Engineering.

Republished with permission of Momentum,
a School of Engineering electronic publication.

By Jayna Miller (CLAS Dec. ’13)

Dr. William Mustain, an assistant professor of Chemical & Biomolecular Engineering, is the recipient of a U.S. Department of Energy (DOE) Office of Science Early Career Award, which is one of the most competitive in the United States, with only 65 awarded annually. The Early Career Research Program supports the research pursuits of exceptional young scientists, and creates career opportunities in various research fields.  Dr. Mustain’s five-year, $800,000 award was presented by the Office of Basic Energy Science.

The award will bring new equipment to the university and fund two graduate and two undergraduate students over the life of the grant.  Dr. Mustain’s proposal, “Room Temperature Electrochemical Upgrading of Methane to Oxygenate Fuels,” will focus on the development of a new type of electrochemical device that converts methane, from natural gas or biogas, to liquid fuels, like methanol, at room temperature.  This low temperature operation is a significant improvement over state-of-the-art methane-to-fuels processes that operate at very high temperatures, sometimes more than 900°C.  They also generally convert methane to syngas then employ a second process to convert the syngas to other chemicals and fuels. These extra steps add both cost and complexity to the process.

According to Dr. Mustain, the research team will focus on understanding the fundamental mechanisms for the transformation of methane to methanol at ultra-low temperatures, bypassing the syngas intermediate,  as well as determining the optimal design conditions to maximize methane conversion and methanol selectivity.

Perhaps the most exciting aspect of this process is that it is able to operate at or near room temperature (20-50°C), which has a number of advantages.  “There will be lower energy required for the process, and much lower cost because you do not need high quality heat and you have a wider range of materials that you can consider,” said Dr. Mustain.  He hopes to leverage all of the work that has been done on other electrochemical devices, like batteries and fuel cells, over the last 20 years to make rapid improvements on his prototype.

There are a variety of practical applications for this research.  For instance, methanol can be used as a direct energy carrier, and as a fuel source for small portable power applications or cars using a direct methanol fuel cell.  Methanol is also one of the top 25 industrial chemicals in the world, which means it has a range of uses.  In addition, it can be easily converted to formaldehyde, which is another top 25 industrial chemical.

Dr. Mustain’s previous research has involved the design of new catalyst materials for fuel cells, capacitors and lithium-ion batteries. He also has received the Illinois Institute of Technology Young Alumni Award. For more about his DOE-funded research, please visit http://science.energy.gov/early-career/.